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Western blot analysis of extracts from HT29 cells untreated or treated with UV, using Phospho-c-Myc-T358 antibody (AP0411).|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.
Phospho-c-Myc-T358 Rabbit pAb
Catalog No：AB-AP0411
Manufacturer：ABclonal
Synonyms：MRTL;MYCC;bHLHe39;c-Myc;MYC
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€150,00 – €410,00
| Product Name: | Phospho-c-Myc-T358 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt’s lymphomas, suggesting its importance in the normal function of this gene. |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding T358 of human c-Myc |
| Gene ID: | 4609 |
| Swiss prot: | P01106 |
| Molecular weight: | 48kDa/50kDa |
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