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Western blot analysis of extracts from HeLa cells using Phospho-ATF4-S245 antibody (AP0309).|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.
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Immunohistochemistry of paraffin-embedded human breast carcinoma using Phospho-ATF4-S245 antibody (AP0309).
Phospho-ATF4-S245 Rabbit pAb
Catalog No：AB-AP0309
Manufacturer：ABclonal
Synonyms：ATF4;CREB-2;CREB2;TAXREB67;TXREB
Applications：WB,IHC
Reactivity：Human
Host：Rabbit
Conjugate：No
€150,00 – €410,00
| Product Name: | Phospho-ATF4-S245 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding S245 of human ATF4 |
| Gene ID: | 468 |
| Swiss prot: | P18848 |
| Molecular weight: | 38kDa |
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