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Western blot analysis of extracts from DU145 cells using Phospho-Androgen Receptor-S213 antibody (AP0306).|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.
Phospho-Androgen Receptor-S213 Rabbit pAb
Catalog No：AB-AP0306
Manufacturer：ABclonal
Synonyms：AIS;AR8;DHTR;HUMARA;HYSP1;KD;NR3C4;SBMA;SMAX1;TFM;AR
Applications：WB,IF
Reactivity：Human
Host：Rabbit
Conjugate：No
€150,00 – €410,00
| Product Name: | Phospho-Androgen Receptor-S213 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding S213 of human Androgen Receptor |
| Gene ID: | 367 |
| Swiss prot: | P10275 |
| Molecular weight: | 44kDa/67kDa/99kDa |
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