Phospho-ACC1-S79 Rabbit pAb
Catalog No:AB-AP0873
Manufacturer:ABclonal
Synonyms:ACACA;ACAC;ACACAD;ACC;ACC1;ACCA
Applications:IHC
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €410,00
Product Name: | Phospho-ACC1-S79 Rabbit pAb |
Category: | Phosphorylated Antibodies |
Description: | Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5′ sequence and encoding distinct isoforms have been found for this gene. |
Immunogen: | A phospho specific peptide corresponding to residues surrounding S79 of human ACC1 |
Gene ID: | 31 |
Swiss prot: | Q13085 |
Molecular weight: | 257kDa/259kDa/265kDa/269kDa |
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