(Phe1,Ser2,Tyr 6)-PAR-1 (1-6) amide (human)
Catalog No：CP-PARP-004B
Manufacturer：CPC Scientific
Size：25 mg
CAS No.：245329-02-6
Formula：C39H60N 10O8
MWt：797
€746,00
| Product Name: | (Phe1,Ser2,Tyr 6)-PAR-1 (1-6) amide (human) |
| Category: | Peptides |
| Three letter sequence: | Phe-Ser-Leu- Leu-Arg-Tyr- NH2 Trifluoroacet ate salt |
| One letter sequence: | FSLLRY-NH2 |
| Description: | This peptide inhibited activation of PAR-2 by trypsin in PAR-2 receptor expressing KNRK cells. Half- maximal inhibition of calcium signaling was observed at about 50 碌M. In contrast, the activation of PAR-2 by SLIGRL-NH2 (PAR-2 (1-6) amide (mouse, rat)) was not inhibited by this peptide. Selective Antagonist for PAR2 Agonist. This peptide blocks trypsin but not SLIGRL-NH2 activation of PAR2 in receptor-expressing KNRK cells. |
| Literature References: | B.Al-Ani et al., J. Pharmacol. Exp. Ther., 300, 702 (2002) S.Wilson et al., Biochem. J., 388, 967 (2005) |
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