Western blot analysis of extracts of various cell lines, using PHC2 antibody (A14610) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
PHC2 Rabbit pAb
Catalog No:AB-A14610
Manufacturer:ABclonal
Synonyms:PHC2;EDR2;HPH2;PH2
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | PHC2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | In Drosophila melanogaster, the ‘Polycomb’ group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein ‘polyhomeotic’ (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 250-323 of human PHC2 (NP_004418.2). |
Gene ID: | 1912 |
Swiss prot: | Q8IXK0 |
Molecular weight: | 30kDa/35kDa/87kDa/90kDa |
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