PF-04995274 [Cas No. 1331782-27-4]
Catalog No:TA-T16481
Manufacturer:TargetMol
CAS No.:1331782-27-4
Formula:C23H32N2O6
MWt:432.51
€30,00 – €227,00
Name: | PF-04995274 |
Category: | Biochemicals |
Description: | PF-04995274 is an effective, high-affinity, and partial serotonin 4 receptor (5-HT4R) agonist. PF-04995274 is brain penetrant and can be used for cognitive disorders associated with Alzheimer’s disease. PF-04995274 has an EC50 range of 0.26-0.47 nM for human 5-HT4A/4B/4D/4E (Ki range of 0.15-0.46 nM). It also has an EC50 range of 0.59-0.65 nM for rat 5-HT4S/4L/4E (Ki of 0.30 nM for rat 5-HT4S). |
Pathway: | GPCR/G Protein,Neuroscience |
Target: | 5-HT Receptor |
Receptor: | 5-HT4 |
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