Western blot analysis of extracts of various cell lines, using PEX19 antibody (A19237) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
PEX19 Rabbit mAb
Catalog No:AB-A19237
Manufacturer:ABclonal
Synonyms:PEX19; D1S2223E; HK33; PBD12A; PMP1; PMPI; PXF; PXMP1; peroxisomal biogenesis factor 19
Applications:WB
Reactivity:Human,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | PEX19 Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant protein of human PEX19. |
Gene ID: | 5824 |
Swiss prot: | P40855 |
Molecular weight: | 35,40kDa |
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