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Western blot analysis of extracts of various cell lines, using PER1 antibody (A8449) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 180s.
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Immunohistochemistry of paraffin-embedded human colon using PER1 Rabbit pAb (A8449) at dilution of 1:100 (40x lens).
PER1 Rabbit pAb
Catalog No：AB-A8449
Manufacturer：ABclonal
Synonyms：PER1;PER;RIGUI;hPER
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | PER1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PER1 (NP_002607.2). |
| Gene ID: | 5187 |
| Swiss prot: | O15534 |
| Molecular weight: | 91kDa/136kDa |
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