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Western blot analysis of extracts of various cell lines, using PDZD3 antibody (A12222) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
PDZD3 Rabbit pAb
Catalog No：AB-A12222
Manufacturer：ABclonal
Synonyms：PDZD3;IKEPP;NHERF4;PDZK2
Applications：WB
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | PDZD3 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).[supplied by OMIM, Mar 2008] |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human PDZD3 (NP_079067.3). |
| Gene ID: | 79849 |
| Swiss prot: | Q86UT5 |
| Molecular weight: | 24kDa/41kDa/52kDa/54kDa/61kDa |
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