Western blot analysis of extracts of various cell lines, using PDX1 antibody (A10173) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
PDX1 Rabbit pAb
Catalog No:AB-A10173
Manufacturer:ABclonal
Synonyms:PDX1;GSF;IDX-1;IPF1;IUF1;MODY4;PAGEN1;PDX-1;STF-1
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | PDX1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PDX1 (NP_000200.1). |
Gene ID: | 3651 |
Swiss prot: | P52945 |
Molecular weight: | 30kDa |
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