Western blot analysis of extracts of various cell lines, using PDE6B antibody (A6942) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
PDE6B Rabbit pAb
Catalog No:AB-A6942
Manufacturer:ABclonal
Synonyms:PDE6B;CSNB3;CSNBAD2;PDEB;RP40;rd1;GMP-PDEbeta
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | PDE6B Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human PDE6B (NP_001138763.1). |
Gene ID: | 5158 |
Swiss prot: | P35913 |
Molecular weight: | 66kDa/98kDa |
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