Western blot analysis of extracts of various cell lines, using PARN antibody (A4002) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 150s.
PARN Rabbit pAb
Catalog No:AB-A4002
Manufacturer:ABclonal
Synonyms:PARN;DAN;DKCB6;PFBMFT4
Applications:WB,IHC,IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | PARN Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene is a 3′-exoribonuclease, with similarity to the RNase D family of 3′-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PARN (NP_002573.1). |
Gene ID: | 5073 |
Swiss prot: | O95453 |
Molecular weight: | 52kDa/66kDa/67kDa/73kDa |
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