p53 (17-26)
Catalog No:CP-CANC-016A
Manufacturer:CPC Scientific
Size:1 mg
MWt:1,252
€76,00
Product Name: | p53 (17-26) |
Category: | Peptides |
Three letter sequence: | Glu-Thr-Phe- Ser-Asp-Leu- Trp-Lys-Leu- Leu |
One letter sequence: | ETFSDLWKLL |
Description: | This peptide is amino acids 17 to 26 fragment of p53, the Mdm-2 binding domain of p53 known also as p53N. This sequence contains all of the residues that contact the binding domain of Mdm-2. The tumor suppressor protein p53 is important in maintaining genome stability and in preventing cancer development. |
Literature References: | Wang, Y. et al. J. Biol. Chem. 281, 24803 (2006) Kanovsky, M. et al. PNAS 98, 12438 (2001). |
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