Western blot analysis of extracts of rat liver, using OX40 antibody (A3646) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
OX40 Rabbit pAb
Catalog No:AB-A3646
Manufacturer:ABclonal
Synonyms:TNFRSF4;ACT35;CD134;IMD16;OX40;TXGP1L
Applications:WB
Reactivity:Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | OX40 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human OX40 (NP_003318.1). |
Gene ID: | 7293 |
Swiss prot: | P43489 |
Molecular weight: | 29kDa |
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