Western blot analysis of extracts of various cell lines, using OPRK1 antibody (A8306) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 15s.
OPRK1 Rabbit pAb
Catalog No:AB-A8306
Manufacturer:ABclonal
Synonyms:OPRK1;K-OR-1;KOR;KOR-1;OPRK
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | OPRK1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human OPRK1 (NP_000903.2). |
Gene ID: | 4986 |
Swiss prot: | P41145 |
Molecular weight: | 33kDa/42kDa |
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