Western blot analysis of extracts of various cell lines, using Oncostatin M Antibody (A6163) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 60s.
Oncostatin M Rabbit pAb
Catalog No:AB-A6163
Manufacturer:ABclonal
Synonyms:OSM
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | Oncostatin M Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-252 of human Oncostatin M (NP_065391.1). |
Gene ID: | 5008 |
Swiss prot: | P13725 |
Molecular weight: | 28kDa |
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