Oltipraz [Cas No. 64224-21-1]
Catalog No：TA-T0153
Manufacturer：TargetMol
Synonyms：NSC 347901,RP 35972
CAS No.：64224-21-1
Formula：C8H6N2S3
MWt：226.34
€43,00 – €178,00
| Name: | Oltipraz |
| Category: | Biochemicals |
| Description: | Oltipraz is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties. Oltipraz induces phase II detoxification enzymes, such as glutathione S transferase (GST) and NAD(P)H: quinone oxidoreductase 1 (NQO1). The induction of detoxification enzymes enhances the detoxification of certain cancer-causing agents, thereby enhancing their elimination and preventing carcinogen-induced DNA damages. Although the exact mechanism through which the anti-angiogenesis effect remains to be fully elucidated, oltipraz maybe able to modulate the expression of a number of angiogenic factors, thereby blocking the sustained and focal neovascularization in multiple tumor cell types. |
| Pathway: | Microbiology & Virology,Angiogenesis,Chromatin/Epigenetic |
| Target: | Reverse Transcriptase inhibitor,HIF |
| Receptor: | Reverse Transcriptase,HIF-1α |
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