Western blot analysis of extracts of HepG2 cells, using OGG1 antibody (A2268) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 90s.
OGG1 Rabbit pAb
Catalog No:AB-A2268
Manufacturer:ABclonal
Synonyms:OGG1;HMMH;HOGG1;MUTM;OGH1
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | OGG1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. |
Immunogen: | A synthetic peptide of human OGG1 |
Gene ID: | 4968 |
Swiss prot: | O15527 |
Molecular weight: | 22kDa/36kDa/38kDa/39kDa/40kDa/45kDa/47kDa |
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