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Western blot analysis of extracts of various cell lines, using NR3C2 antibody (A3308) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded human liver cancer using NR3C2 Rabbit pAb (A3308) at dilution of 1:100 (40x lens).
NR3C2 Rabbit pAb
Catalog No：AB-A3308
Manufacturer：ABclonal
Synonyms：NR3C2;MCR;MLR;MR;NR3C2VIT
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | NR3C2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 800 to the C-terminus of human NR3C2 (NP_001159576.1). |
| Gene ID: | 4306 |
| Swiss prot: | P08235 |
| Molecular weight: | 75kDa/94kDa/107kDa |
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