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Western blot analysis of extracts of various cell lines, using NR1H2 antibody (A16291) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3min.
NR1H2 Rabbit pAb
Catalog No：AB-A16291
Manufacturer：ABclonal
Synonyms：NR1H2;LXR-b;LXRB;NER;NER-I;RIP15;UNR
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | NR1H2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010] |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human NR1H2 (NP_009052.3). |
| Gene ID: | 7376 |
| Swiss prot: | P55055 |
| Molecular weight: | 39kDa/50kDa |
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