Western blot analysis of extracts of SH-SY5Y cells, using NPY antibody (A3178) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 180s.
NPY Rabbit pAb
Catalog No:AB-A3178
Manufacturer:ABclonal
Synonyms:NPY;PYY4
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | NPY Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-97 of human NPY (NP_000896.1). |
Gene ID: | 4852 |
Swiss prot: | P01303 |
Molecular weight: | 10kDa |
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