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Western blot analysis of extracts of various cell lines, using NOD2 Rabbit pAb (A15992) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 60s.
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Immunohistochemistry of paraffin-embedded human colon using NOD2 Rabbit pAb (A15992) at dilution of 1:100 (40x lens).
NOD2 Rabbit pAb
Catalog No：AB-A15992
Manufacturer：ABclonal
Synonyms：NOD2;ACUG;BLAU;BLAUS;CARD15;CD;CLR16.3;IBD1;NLRC2;NOD2B;PSORAS1;YAOS
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | NOD2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 611-910 of human NOD2 (NP_071445.1). |
| Gene ID: | 64127 |
| Swiss prot: | Q9HC29 |
| Molecular weight: | 22kDa/112kDa/115kDa |
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