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Western blot analysis of extracts of various cell lines, using NOD1 antibody (A1246) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 120s.
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Immunohistochemistry of paraffin-embedded human mammary cancer using NOD1 antibody (A1246) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded rat ovary using NOD1 antibody (A1246) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse kidney using NOD1 antibody (A1246) at dilution of 1:100 (40x lens).
NOD1 Rabbit pAb
Catalog No：AB-A1246
Manufacturer：ABclonal
Synonyms：NOD1;CARD4;CLR7.1;NLRC1
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | NOD1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5′ UTR have been described, but the full-length nature of these variants has not been determined. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human NOD1 (NP_006083.1). |
| Gene ID: | 10392 |
| Swiss prot: | Q9Y239 |
| Molecular weight: | 27kDa/107kDa |
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