Western blot analysis of extracts of rat spleen, using NLRP12 antibody (A14519) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
NLRP12 Rabbit pAb
Catalog No:AB-A14519
Manufacturer:ABclonal
Synonyms:NLRP12;CLR19.3;FCAS2;NALP12;PAN6;PYPAF7;RNO;RNO2
Applications:WB
Reactivity:Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | NLRP12 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 862-1062 of human NLRP12 (NP_001264055.1). |
Gene ID: | 91662 |
Swiss prot: | P59046 |
Molecular weight: | 31kDa/101kDa/107kDa/113kDa/114kDa/120kDa |
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