Western blot analysis of extracts of NCI-H460 cells, using NKX2-1 antibody (A3097) at 1:500 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
NKX2-1 Rabbit pAb
Catalog No:AB-A3097
Manufacturer:ABclonal
Synonyms:NKX2-1;BCH;BHC;NK-2;NKX2.1;NKX2A;NMTC1;T/EBP;TEBP;TITF1;TTF-1;TTF1
Applications:WB
Reactivity:Human,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | NKX2-1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias ‘TTF1’ with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. |
Immunogen: | A synthetic peptide of human NKX2-1 |
Gene ID: | 7080 |
Swiss prot: | P43699 |
Molecular weight: | 38kDa/41kDa |
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