Western blot analysis of extracts of various cell lines, using NFAT2 antibody (A1539) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
NFAT2 Rabbit pAb
Catalog No:AB-A1539
Manufacturer:ABclonal
Synonyms:NF-ATC;NF-ATc1.2;NFAT2;NFATc;NFATC1
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | NFAT2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human NFAT2 (NP_765978.1). |
Gene ID: | 4772 |
Swiss prot: | O95644 |
Molecular weight: | 38kDa/74- 88kDa/100-101kDa |
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