Western blot analysis of extracts of various cell lines, using NF-κB2 antibody (A11163) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
NF-κB2 Rabbit pAb
Catalog No:AB-A11163
Manufacturer:ABclonal
Synonyms:CVID10;H2TF1;LYT-10;LYT10;NF-kB2;p100;p49/p100;p52
Applications:WB,IF
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | NF-κB2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 690-899 of human NF-κB2 (NP_002493.3). |
Gene ID: | 4791 |
Swiss prot: | Q00653 |
Molecular weight: | 47kDa/96kDa |
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