Neuromedin S (human)
Catalog No:CP-NEUP-007A
Manufacturer:CPC Scientific
Size:0.5 mg
Formula:C173H265 N53O44
MWt:3,791
€232,00
Product Name: | Neuromedin S (human) |
Category: | Peptides |
Three letter sequence: | Ile-Leu-Gln- Arg-Gly-Ser- Gly-Thr-Ala- Ala-Val-Asp- Phe-Thr-Lys- Lys-Asp-His- Thr-Ala-Thr- Trp-Gly-Arg- Pro-Phe- Phe-Leu- Phe-Arg-Pro- Arg-Asn-NH2 Trifluoroacet ate salt |
One letter sequence: | ILQRGSGTAAV DFTKKDHTAT WGRPFFLFRP RN-NH2 |
Description: | This peptide was originally isolated from rat brain as an endogenous ligand for two orphan G protein-coupled receptors FM- 3/GPR66 and FM- 4/TGR-1, which have been identified as neuromedin U (NMU) receptors. hNMS-33 is specifically expressed in the suprachiasmatic nuclei (SCN) of the hypothalamus. It has been shown that NMS is implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions. |
Literature References: | K.Mori et al., EMBO J., 24, 325 (2005) |
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