Western blot analysis of extracts of various cell lines, using MYOT antibody (A6439) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 90s.
MYOT Rabbit pAb
Catalog No:AB-A6439
Manufacturer:ABclonal
Synonyms:MYOT;LGMD1;LGMD1A;MFM3;TTID;TTOD;myotilin
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | MYOT Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 259-314 of human MYOT (NP_001129412.1). |
Gene ID: | 9499 |
Swiss prot: | Q9UBF9 |
Molecular weight: | 35kDa/55kDa |
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