Western blot analysis of extracts of various cell lines, using Myosin heavy chain Rabbit mAb (A4963) at 1:5000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
Myosin heavy chain Rabbit mAb
Catalog No:AB-A4963
Manufacturer:ABclonal
Synonyms:CMD1S, CMH1, MPD1, MYHCB, SPMD, SPMM
Applications:WB,IHC,IF
Reactivity:Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | Myosin heavy chain Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy. [provided by RefSeq, Jul 2008] |
Immunogen: | A synthesized peptide derived from human Myosin heavy chain |
Gene ID: | 4625/4624 |
Swiss prot: | P12883/P13533 |
Molecular weight: | 224kDa |
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