Myelin Oligodendrocyt e Glycoprotein (35-55) (human) MOG (35-55) (human)
Catalog No:CP-MOG-002A
Manufacturer:CPC Scientific
Size:0.5 mg
CAS No.:163158-19-8
Formula:C120H179 N35O28S
MWt:2,592
€93,00
Product Name: | Myelin Oligodendrocyt e Glycoprotein (35-55) (human) MOG (35-55) (human) |
Category: | Peptides |
Three letter sequence: | H-Met-Glu- Val-Gly-Trp- Tyr-Arg-Pro- Pro-Phe-Ser- Arg-Val-Val- His-Leu-Tyr- Arg-Asn-Gly- Lys-OH Trifluoroacet ate salt |
One letter sequence: | MEVGWYRPPF SRVVHLYRNG K-OH |
Description: | In contrast to the encephalitogenic rat homolog, this peptide is not a major T-cell epitope in multiple sclerosis propably due to its lower amount of helical structure formed when dissolved in micellar sodium dodecyl sulfate. This peptide induced anti- MOG(35-55) autoantibody production in C57BL/6 mice. |
Literature References: | N.Kerlero de Rosbo et al., Eur. J. Immunol., 27, 3059 (1997) S.Albouz-Abo et al., Eur. J. Biochem., 246, 59 (1997) M.F.Mesleh et al., Neurobiol. Dis., 9, 160 (2002) Oliver, A. J. Immunology 171, 462 (2003) Stromnes, I. et al. Nature protocols 1, 1810 (2006) |
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