Jervine [Cas No. 469-59-0]
Catalog No:TA-T3363
Manufacturer:TargetMol
Synonyms:11-Ketocyclopamine,Iervin,Jerwiny
CAS No.:469-59-0
Formula:C27H39NO3
MWt:425.61
€55,00 – €1.520,00
Name: | Jervine |
Category: | Biochemicals |
Description: | The biological activity of Jervine is mediated via its interaction with the 7 passes transmembrane protein Smoothened. Jervine binds with and inhibits smoothened, which is an integral part of the Hedgehog signaling pathways. With smoothened inhibited, the GLI1 transcription cannot be activated and Hedgehog target genes cannot be transcribed. |
Pathway: | GPCR/G Protein, Stem Cells |
Target: | Hedgehog/Smoothened inhibitor |
Receptor: | Hedgehog, Smoothened |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No:TA-Fr14438
Manufacturer:TargetMol
Synonyms:4-Methylbenzoic acid
CAS No.:99-94-5
Formula:C8H8O2
MWt:136.15
€43,00 – €97,00
Catalog No:TA-Fr14127
Manufacturer:TargetMol
Synonyms:2,3-Dihydrobenzofuran
CAS No.:496-16-2
Formula:C8H8O
MWt:120.15
€39,00 – €50,00
Catalog No:TA-Fr13883
Manufacturer:TargetMol
CAS No.:1798-09-0
Formula:C9H10O3
MWt:166.18
€42,00 – €50,00
Catalog No:TA-Fr13711
Manufacturer:TargetMol
CAS No.:532-24-1
Formula:C8H13NO
MWt:139.19
€42,00 – €50,00
Catalog No:TA-Fr12290
Manufacturer:TargetMol
CAS No.:20280-81-3
Formula:C10H8O3
MWt:176.17
€50,00 – €60,00
Privacy Overview
Cookie | Duration | Description |
---|---|---|
cookielawinfo-checkbox-analytics | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Analytics". |
cookielawinfo-checkbox-functional | 11 months | The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". |
cookielawinfo-checkbox-necessary | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookies is used to store the user consent for the cookies in the category "Necessary". |
cookielawinfo-checkbox-others | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Other. |
cookielawinfo-checkbox-performance | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Performance". |
viewed_cookie_policy | 11 months | The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data. |