Western blot analysis of extracts of SW620 cells, using MSH3 Rabbit pAb (A5681) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 180s.
MSH3 Rabbit pAb
Catalog No:AB-A5681
Manufacturer:ABclonal
Synonyms:MSH3;DUP;FAP4;MRP1
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | MSH3 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 617-761 of human MSH3 (NP_004696.2). |
Gene ID: | 4437 |
Swiss prot: | P20585 |
Molecular weight: | 127kDa |
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