MMP14/MT1-MMP Rabbit pAb
Catalog No：AB-A15691
Manufacturer：ABclonal
Synonyms：MMP14;MMP-14;MMP-X1;MT-MMP;MT-MMP 1;MT1-MMP;MT1MMP;MTMMP1;WNCHRS;MT-MMP1
Applications：IF
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | MMP14/MT1-MMP Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP’s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. |
| Immunogen: | A synthetic peptide of human MMP14/MT1-MMP |
| Gene ID: | 4323 |
| Swiss prot: | P50281 |
| Molecular weight: | 65kDa |
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