Western blot analysis of extracts of various cell lines, using MMP11 Rabbit mAb (A11088) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
MMP11 Rabbit mAb
Catalog No:AB-A11088
Manufacturer:ABclonal
Synonyms:SL-3, ST3, STMY3
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | MMP11 Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008] |
Immunogen: | A synthesized peptide derived from human MMP11 |
Gene ID: | 4320 |
Swiss prot: | P24347 |
Molecular weight: | 55kDa |
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