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Immunohistochemistry of paraffin-embedded human breast cancer using MLKL antibody (A13452) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human uterine cancer using MLKL antibody (A13452) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human tonsil using MLKL antibody (A13452) at dilution of 1:100 (40x lens).
MLKL Rabbit pAb
Catalog No：AB-A13452
Manufacturer：ABclonal
Synonyms：MLKL;hMLKL
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | MLKL Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene. |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of mouse MLKL (NP_001297542.1). |
| Gene ID: | 74568 |
| Swiss prot: | |
| Molecular weight: | 53kDa/54kDa |
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