Western blot analysis of extracts of various cell lines, using MICA antibody (A19256) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
Western blot analysis of extracts of Rat stomach, using MICA antibody (A19256) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 180s.
MICA Rabbit mAb
Catalog No:AB-A19256
Manufacturer:ABclonal
Synonyms:MICA; MIC-A; PERB11.1; MHC class I polypeptide-related sequence A
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€195,00 – €485,00
Product Name: | MICA Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. |
Immunogen: | Recombinant protein of human MICA. |
Gene ID: | 100507436 |
Swiss prot: | Q29983 |
Molecular weight: | 42-70kDa |
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