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Western blot analysis of extracts of various cell lines, using MIB1/DIP1 antibody (A8588) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
MIB1/DIP1 Rabbit pAb
Catalog No：AB-A8588
Manufacturer：ABclonal
Synonyms：MIB1;DIP-1;DIP1;LVNC7;MIB;ZZANK2;ZZZ6
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | MIB1/DIP1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 560-860 of human MIB1/DIP1 (NP_065825.1). |
| Gene ID: | 57534 |
| Swiss prot: | Q86YT6 |
| Molecular weight: | 110kDa |
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