Methyl-RB-H281 Rabbit pAb
Catalog No:AB-A18818
Manufacturer:ABclonal
Synonyms:RB1; OSRC; PPP1R130; RB; p105-Rb; pRb; pp110; RB transcriptional corepressor 1
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€110,00 – €410,00
Product Name: | Methyl-RB-H281 Rabbit pAb |
Category: | Methylated Antibodies |
Description: | The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. |
Immunogen: | Recombinant protein of human Methyl-RB-H281. |
Gene ID: | 5925 |
Swiss prot: | P06400 |
Molecular weight: | 106kDa |
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