Western blot analysis of extracts of various cell lines, using MED23 Antibody (A10163) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
MED23 Rabbit pAb
Catalog No:AB-A10163
Manufacturer:ABclonal
Synonyms:MED23;ARC130;CRSP130;CRSP133;CRSP3;DRIP130;MRT18;SUR-2;SUR2
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | MED23 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 890-1110 of human MED23 (NP_001257450.1). |
Gene ID: | 9439 |
Swiss prot: | Q9ULK4 |
Molecular weight: | 54kDa/100kDa/155kDa/156kDa |
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