Western blot analysis of extracts of various cell lines, using MCM8 antibody (A12922) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
MCM8 Rabbit pAb
Catalog No:AB-A12922
Manufacturer:ABclonal
Synonyms:MCM8;C20orf154;POF10;dJ967N21.5
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | MCM8 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the mini-chromosome maintenance proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the mini-chromosome maintenance proteins. The encoded protein may interact with other mini-chromosome maintenance proteins and play a role in DNA replication. This gene may be associated with length of reproductive lifespan and menopause. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 591-840 of human MCM8 (NP_115874.3). |
Gene ID: | 84515 |
Swiss prot: | Q9UJA3 |
Molecular weight: | 88kDa/91kDa/93kDa/97kDa |
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