MBTPS1 Rabbit pAb
Catalog No:AB-A13379
Manufacturer:ABclonal
Synonyms:MBTPS1;PCSK8;S1P;SKI-1
Applications:IHC,IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | MBTPS1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 803-1052 of human MBTPS1 (NP_003782.1). |
Gene ID: | 8720 |
Swiss prot: | Q14703 |
Molecular weight: | 117kDa |
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