Western blot analysis of extracts of THP-1 cells, using MATK antibody (A6651) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
MATK Rabbit pAb
Catalog No:AB-A6651
Manufacturer:ABclonal
Synonyms:MATK;CHK;CTK;HHYLTK;HYL;HYLTK;Lsk
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | MATK Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 352-466 of human MATK (NP_647611.1). |
Gene ID: | 4145 |
Swiss prot: | P42679 |
Molecular weight: | 51kDa/56kDa |
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