2,5-Dihydroxyacetophenone [Cas No. 490-78-8]
Catalog No：TA-TCS2170
Manufacturer：TargetMol
Synonyms：DHAP,2-Acetylhydroquinone,Quinacetophenone,Acetylhydroquinone,2,5-Dihydroxyacetophenone
CAS No.：490-78-8
Formula：C8H8O3
MWt：152.14
€28,00 – €54,00
| Name: | 2-5-dihydroxyacetophenone |
| Category: | Biochemicals |
| Description: | 1. 2, 5-Dihydroxyacetophenone possess anti-anxiety, and neuroprotective qualities. 2. 2, 5-Dihydroxyacetophenone treatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPKs, it also can potentiate the pro-apoptotic and anti-proliferative effects of bortezomib in U266 cells. 3. 2, 5-Dihydroxyacetophenone has anti-inflammatory activity in activated macrophages, raising the possibility that this compound has a therapeutic potential for inflammatory conditions. 4. 2, 5-Dihydroxyacetophenone is an uncompetitive inhibitor of murine tyrosinase (K(I) 0.28mm), it strongly inhibits both melanogenesis and cellular tyrosinase activity in vitro in 3-isobutyl-1-methylxanthin-stimulated B16 mouse melanoma cells or in vivo in zebrafish and mouse models. |
| Pathway: | Proteases & Proteasome |
| Target: | Tyrosinase |
| Receptor: | Tyrosinase |
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