[Lys(Me2)382]- p53 (377-387); p53K382Me2
Catalog No:CP-CANC-013A
Manufacturer:CPC Scientific
Size:0.25 mg
MWt:1,405
€141,00
Product Name: | [Lys(Me2)382]- p53 (377-387); p53K382Me2 |
Category: | Peptides |
Three letter sequence: | Thr-Ser-Arg- His-Lys- Lys(Me2)- Leu-Met- Phe-Lys-Thr |
One letter sequence: | TSRHK-K(Me2)- LMFKT |
Description: | p53K382Me2 is derived from amino acid residues 377- 387 of human p53 tumor suppressor protein, with dimethylation at Lys382. DNA damage induces increased levels of this peptide, which is recognized by p53- binding protein 1 (53BP1). 53BP1 interacts with p53 and modulates its transactivation. |
Literature References: | Kachirskaia, I. et al. J Biol Chem 283, 34660 (2008). |
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