[Lys(Me2)372]- p53 (368-393), p53 K372(Me2), biotin-labeled, human
Catalog No:CP-CANC-012A
Manufacturer:CPC Scientific
Size:0.25 mg
MWt:3,467
€146,00
Product Name: | [Lys(Me2)372]- p53 (368-393), p53 K372(Me2), biotin-labeled, human |
Category: | Peptides |
Three letter sequence: | Biotin-Lys- Gly-Gly-His- Leu-Lys-Ser- Lys(Me2)- Lys-Gly-Gln- Ser-Thr-Ser- Arg-His-Lys- Lys-Leu-Met- Phe-Lys-Thr- Glu-Gly-Pro- Asp-Ser-Asp- NH2 |
One letter sequence: | Biotin- KGGHLKS- K(Me2)- KGQSTSRHKKL MFKTEGPDSD- NH2 |
Description: | This is a biotin- labeled and amidated peptide derived from residues 368-393 of human p53 tumor suppressor protein with dimethylation at Lys372 and additional KGW residues on its N- terminus. Methylation at Lys372 activates p53 and induces upregulation of target gene p21. Methylation at Lys372 also inhibits Lys370 methylation by interfering with Smyd2, a lysine methyltransferase, and p53 interaction. Lys 370 methylation reduces p53 transcriptional |
Literature References: | Huang, J. et al. Nature 440, 629 (2006). |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No:AB-RP00272
Manufacturer:ABclonal
Synonyms:BB2 ;CD54 ;ICAM-1 ;P3.58
Expression Host:HEK293 cells
€30,00 – €475,00
Catalog No:AB-RP00198
Manufacturer:ABclonal
Synonyms:AIM,API6,PRO229,SP-ALPHA,Spalpha
Expression Host:HEK293 cells
€55,00 – €85,00
Catalog No:AB-RP00188
Manufacturer:ABclonal
Synonyms:APN,CD13,GP150,LAP1,P150,PEPN
Expression Host:HEK293 cells
€60,00 – €745,00
Catalog No:AB-RP00164
Manufacturer:ABclonal
Synonyms:C1qR(P),C1QR1,C1qRP,CDw93,dJ737E23.1,ECSM3,MXRA4
Expression Host:HEK293 cells
€80,00 – €340,00
Catalog No:AB-RP00131
Manufacturer:ABclonal
Synonyms:CD66D;CEA;CGM1;W264;W282
Expression Host:HEK293 cells
€105,00 – €1.065,00
Catalog No:AB-RP00115
Manufacturer:ABclonal
Synonyms:MIG20a;NTRKR3;TKT;TYRO10
Expression Host:HEK293 cells
€85,00 – €705,00
Privacy Overview
Cookie | Duration | Description |
---|---|---|
cookielawinfo-checkbox-analytics | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Analytics". |
cookielawinfo-checkbox-functional | 11 months | The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". |
cookielawinfo-checkbox-necessary | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookies is used to store the user consent for the cookies in the category "Necessary". |
cookielawinfo-checkbox-others | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Other. |
cookielawinfo-checkbox-performance | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Performance". |
viewed_cookie_policy | 11 months | The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data. |