Picropodophyllotoxin [Cas No. 17434-18-3]
Catalog No：TA-T3S0027
Manufacturer：TargetMol
Synonyms：Picropodophyllin,AXL 1717
CAS No.：17434-18-3
Formula：C22H22O8
MWt：414.41
€50,00 – €516,00
| Name: | Picropodophyllotoxin |
| Category: | Biochemicals |
| Description: | Picropodophyllin is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential antineoplastic activity. Picropodophyllin specifically inhibits the activity and downregulates the cellular expression of IGF1R without interfering with activities of other growth factor receptors, such as receptors for insulin, epidermal growth factor, platelet-derived growth factor, fibroblast growth factor and mast/stem cell growth factor (KIT). This agent shows potent activity in the suppression o f tumor cell proliferation and the induction of tumor cell apoptosis. IGF1R, a receptor tyrosine kinase overexpressed in a variety of human cancers, plays a critical role in the growth and survival of many types of cancer cells. |
| Pathway: | Tyrosine Kinase/Adaptors |
| Target: | IGF-1R |
| Receptor: | IGF-1R |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No：TA-Fr14127
Manufacturer：TargetMol
Synonyms：2,3-Dihydrobenzofuran
CAS No.：496-16-2
Formula：C8H8O
MWt：120.15
€39,00 – €50,00
Catalog No：TA-Fr12662
Manufacturer：TargetMol
CAS No.：35817-27-7
Formula：C11H10O3
MWt：190.2
€50,00 – €90,00
Catalog No：TA-Fr12596
Manufacturer：TargetMol
CAS No.：3949-36-8
Formula：C11H8O3
MWt：188.1
€50,00
Catalog No：TA-Fr12339
Manufacturer：TargetMol
Synonyms：Anisylacetone
CAS No.：104-20-1
Formula：C11H14O2
MWt：178.2
€39,00 – €50,00
Catalog No：TA-Fr12290
Manufacturer：TargetMol
CAS No.：20280-81-3
Formula：C10H8O3
MWt：176.17
€50,00 – €60,00
Catalog No：TA-Fr12277
Manufacturer：TargetMol
CAS No.：13252-83-0
Formula：C10H8O3
MWt：176.1
€50,00 – €80,00