Midostaurin [Cas No. 120685-11-2]
Catalog No：TA-T3211
Manufacturer：TargetMol
Synonyms：CGP 41251,PKC412,CGP41231,N-Benzoylstaurosporine
CAS No.：120685-11-2
Formula：C35H30N4O4
MWt：570.64
€60,00 – €1.150,00
| Name: | Midostaurin |
| Category: | Biochemicals |
| Description: | PKC412(Midostaurin, CGP41231, CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platelet-derived growth factor receptor (PDGFR) and FMS-like tyrosine kinase 3 (FLT3) tyrosine kinases, which may result in disruption of the cell cycle, inhibition of proliferation, apoptosis, and inhibition of angiogenesis in susceptible tumors. |
| Pathway: | Cytoskeletal Signaling, Others |
| Target: | Others inhibitor, PKC inhibitor |
| Receptor: | PPK, PKCα, PKCβ1, PKCβ2, PKCγ |
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