LMTK2 Rabbit pAb
Catalog No:AB-A15403
Manufacturer:ABclonal
Synonyms:LMTK2;AATYK2;BREK;KPI-2;KPI2;LMR2;PPP1R100;cprk;hBREK
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €325,00
Product Name: | LMTK2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1100-1300 of human LMTK2 (NP_055731.2). |
Gene ID: | 22853 |
Swiss prot: | Q8IWU2 |
Molecular weight: | 164kDa |
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